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Proper Infant Formula Preparation

  • Writer: Amy Berg, LM, NCS, PPD
    Amy Berg, LM, NCS, PPD
  • 4 days ago
  • 2 min read

Bringing home your baby comes with many new routines, feeding being one of the most important. Whether you're exclusively formula-feeding or supplementing, safe infant formula preparation is essential to your baby’s health. This guide offers evidence-based recommendations to ensure you’re giving your baby a safe and nutritious start.


Father gently feeding newborn baby with a bottle, bonding during feeding time.

🍼 Why Proper Preparation Matters

Improper formula preparation can lead to nutritional imbalances or expose your baby to harmful bacteria like Cronobacter sakazakii. While rare, infections can be serious or even fatal in newborns. Following safe preparation guidelines significantly reduces these risks.


💧 1. Choose the Right Water

According to the World Health Organization (WHO) and Centers for Disease Control and Prevention (CDC), powdered infant formula is not sterile. To reduce the risk of bacterial infection:

  • Boil water and let it cool slightly to no less than 158°F (70°C) before mixing with powdered formula. This temperature kills most harmful bacteria.

  • After mixing, cool the bottle by running it under cold water or placing it in a bowl of ice water until it’s safe to feed (around body temperature).

  • Use potable, safe tap water or bottled water labeled for infant use.

  • Avoid well water, softened water, or mineral water unless approved by your pediatrician.


This step is especially important for:

  • Babies under 3 months old

  • Premature babies

  • Babies with weakened immune systems


⚖️ 2. Measure Precisely

  • Follow the manufacturer’s instructions on the label exactly.

  • Use only the scoop provided in the formula container.

  • Over-diluted formula can result in inadequate nutrition, while overly concentrated formula can strain a baby’s kidneys.


🧼 3. Prioritize Hygiene

  • Wash your hands thoroughly before handling bottles or formula.

  • Sterilize bottles, nipples, caps, and mixing utensils before the first use and regularly thereafter.

  • Clean and sanitize your preparation area before each feed.


⏱️ 4. Mix and Store Safely

  • Ideally, mix formula just before feeding.

  • If preparing in advance, follow these storage guidelines:

    • Refrigerate mixed formula at 40°F (4°C) or lower and use within 24 hours.

    • Formula left at room temperature should be used within 2 hours.

    • Once feeding begins, discard any unused formula after 1 hour.

  • Never heat bottles in the microwave; use warm water baths to avoid dangerous hot spots.


🌡️ 5. Check the Temperature

Before feeding, test a few drops of formula on the inside of your wrist. It should feel warm, not hot.


💡 Final Thoughts

Your baby's safety starts with simple, mindful routines. From choosing the right water to understanding storage times, these small steps help ensure every bottle is safe and nourishing. When in doubt, consult your pediatrician or a certified newborn care specialist for personalized guidance.


📚 Research & Resources




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©2019 by Beyond the Third Trimester | Midwife, Newborn Care Specialist & Postpartum Doula | San Diego, CA

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